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A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding
The c-Myb protein is a transcriptional regulator initially identified by homology to the v-Myb oncoprotein, and has since been implicated in human cancer. The most highly conserved portion of the c-Myb protein is the DNA-binding domain which consists of three imperfect repeats. Many other proteins c...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572630/ https://www.ncbi.nlm.nih.gov/pubmed/18840288 http://dx.doi.org/10.1186/1476-4598-7-77 |