AMIN domains have a predicted role in localization of diverse periplasmic protein complexes

We describe AMIN (Amidase N-terminal domain), a novel protein domain found specifically in bacterial periplasmic proteins. AMIN domains are widely distributed among peptidoglycan hydrolases and transporter protein families. Based on experimental data, contextual information and phyletic profiles, we...

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Detalles Bibliográficos
Autores principales: de Souza, Robson Francisco, Anantharaman, Vivek, de Souza, Sandro José, Aravind, L., Gueiros-Filho, Frederico J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Discovery Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572700/
https://www.ncbi.nlm.nih.gov/pubmed/18723522
http://dx.doi.org/10.1093/bioinformatics/btn449
Descripción
Sumario:We describe AMIN (Amidase N-terminal domain), a novel protein domain found specifically in bacterial periplasmic proteins. AMIN domains are widely distributed among peptidoglycan hydrolases and transporter protein families. Based on experimental data, contextual information and phyletic profiles, we suggest that AMIN domains mediate the targeting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. Contact: fgueiros@iq.usp.br Supplementary information: Supplementary data are available at Bioinformatics online.

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