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INTREPID—INformation-theoretic TREe traversal for Protein functional site IDentification

Motivation: Identification of functionally important residues in proteins plays a significant role in biological discovery. Here, we present INTREPID—an information–theoretic approach for functional site identification that exploits the information in large diverse multiple sequence alignments (MSAs...

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Detalles Bibliográficos
Autores principales: Sankararaman, Sriram, Sjölander, Kimmen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572704/
https://www.ncbi.nlm.nih.gov/pubmed/18776193
http://dx.doi.org/10.1093/bioinformatics/btn474