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Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

RbAp46 and RbAp48 (pRB-associated proteins p46 and p48, also known as RBBP7 and RBBP4, respectively) are highly homologous histone chaperones that play key roles in establishing and maintaining chromatin structure. We report here the crystal structure of human RbAp46 bound to histone H4. RbAp46 fold...

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Detalles Bibliográficos
Autores principales: Murzina, Natalia V., Pei, Xue-Yuan, Zhang, Wei, Sparkes, Mike, Vicente-Garcia, Jose, Pratap, J. Venkatesh, McLaughlin, Stephen H., Ben-Shahar, Tom Rolef, Verreault, Alain, Luisi, Ben F., Laue, Ernest D.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572730/
https://www.ncbi.nlm.nih.gov/pubmed/18571423
http://dx.doi.org/10.1016/j.str.2008.05.006