Synthesis and Evaluation of the Cytotoxicity of Apoptolidinones A and D

[Image: see text] Apoptolidins A−D are microbial secondary metabolites shown to be selectively cytotoxic against several cancer cell lines and noncytotoxic against normal cells. Total syntheses of apoptolidinones A and D are reported. The efficient synthetic strategy leading to the apoptolidinones f...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghidu, Victor P., Wang, Jingqi, Wu, Bin, Liu, Qingsong, Jacobs, Aaron, Marnett, Lawrence J., Sulikowski, Gary A.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572754/
https://www.ncbi.nlm.nih.gov/pubmed/18543990
http://dx.doi.org/10.1021/jo800545r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572754/
https://www.ncbi.nlm.nih.gov/pubmed/18543990
http://dx.doi.org/10.1021/jo800545r

Ejemplares similares