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Synthesis and Evaluation of the Cytotoxicity of Apoptolidinones A and D

[Image: see text] Apoptolidins A−D are microbial secondary metabolites shown to be selectively cytotoxic against several cancer cell lines and noncytotoxic against normal cells. Total syntheses of apoptolidinones A and D are reported. The efficient synthetic strategy leading to the apoptolidinones f...

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Detalles Bibliográficos
Autores principales:	Ghidu, Victor P., Wang, Jingqi, Wu, Bin, Liu, Qingsong, Jacobs, Aaron, Marnett, Lawrence J., Sulikowski, Gary A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2008
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572754/ https://www.ncbi.nlm.nih.gov/pubmed/18543990 http://dx.doi.org/10.1021/jo800545r

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