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Expression Patterns of Protein Kinases Correlate with Gene Architecture and Evolutionary Rates

BACKGROUND: Protein kinase (PK) genes comprise the third largest superfamily that occupy ∼2% of the human genome. They encode regulatory enzymes that control a vast variety of cellular processes through phosphorylation of their protein substrates. Expression of PK genes is subject to complex transcr...

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Detalles Bibliográficos
Autores principales: Ogurtsov, Aleksey Y., Mariño-Ramírez, Leonardo, Johnson, Gibbes R., Landsman, David, Shabalina, Svetlana A., Spiridonov, Nikolay A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572838/
https://www.ncbi.nlm.nih.gov/pubmed/18974838
http://dx.doi.org/10.1371/journal.pone.0003599