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Expression Patterns of Protein Kinases Correlate with Gene Architecture and Evolutionary Rates
BACKGROUND: Protein kinase (PK) genes comprise the third largest superfamily that occupy ∼2% of the human genome. They encode regulatory enzymes that control a vast variety of cellular processes through phosphorylation of their protein substrates. Expression of PK genes is subject to complex transcr...
Autores principales: | Ogurtsov, Aleksey Y., Mariño-Ramírez, Leonardo, Johnson, Gibbes R., Landsman, David, Shabalina, Svetlana A., Spiridonov, Nikolay A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572838/ https://www.ncbi.nlm.nih.gov/pubmed/18974838 http://dx.doi.org/10.1371/journal.pone.0003599 |
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