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Estimation of significance thresholds for genomewide association scans
The question of what significance threshold is appropriate for genomewide association studies is somewhat unresolved. Previous theoretical suggestions have yet to be validated in practice, whereas permutation testing does not resolve a discrepancy between the genomewide multiplicity of the experimen...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573032/ https://www.ncbi.nlm.nih.gov/pubmed/18300295 http://dx.doi.org/10.1002/gepi.20297 |