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Ectodomain Lysines and Suramin Block of P2X(1) Receptors

P2X(1) receptors belong to a family of cation channels gated by extracellular ATP; they are found inter alia in smooth muscle, platelets, and immune cells. Suramin has been widely used as an antagonist at P2X receptors, and its analog 4,4′,4″,4‴-[carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino...

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Detalles Bibliográficos
Autores principales: Sim, Joan A., Broomhead, Helen E., North, R. Alan
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573084/
https://www.ncbi.nlm.nih.gov/pubmed/18765669
http://dx.doi.org/10.1074/jbc.M802523200