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Cross-species comparison of biological themes and underlying genes on a global gene expression scale in a mouse model of colorectal liver metastasis and in clinical specimens

BACKGROUND: Invasion-related genes over-expressed by tumor cells as well as by reacting host cells represent promising drug targets for anti-cancer therapy. Such candidate genes need to be validated in appropriate animal models. RESULTS: This study examined the suitability of a murine model (CT26/Ba...

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Detalles Bibliográficos
Autores principales: Bandapalli, Obul Reddy, Kahlert, Christoph, Hellstern, Victoria, Galindo, Luis, Schirmacher, Peter, Weitz, Jürgen, Brand, Karsten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573898/
https://www.ncbi.nlm.nih.gov/pubmed/18823562
http://dx.doi.org/10.1186/1471-2164-9-448