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Kinome-Wide RNAi Screen Implicates at Least 5 Host Hepatocyte Kinases in Plasmodium Sporozoite Infection

Plasmodium sporozoites, the causative agent of malaria, are injected into their vertebrate host through the bite of an infected Anopheles mosquito, homing to the liver where they invade hepatocytes to proliferate and develop into merozoites that, upon reaching the bloodstream, give rise to the clini...

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Detalles Bibliográficos
Autores principales: Prudêncio, Miguel, Rodrigues, Cristina D., Hannus, Michael, Martin, Cécilie, Real, Eliana, Gonçalves, Lígia A., Carret, Céline, Dorkin, Robert, Röhl, Ingo, Jahn-Hoffmann, Kerstin, Luty, Adrian J. F., Sauerwein, Robert, Echeverri, Christophe J., Mota, Maria M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574010/
https://www.ncbi.nlm.nih.gov/pubmed/18989463
http://dx.doi.org/10.1371/journal.ppat.1000201