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Virus growth and antibody responses following respiratory tract infection of ferrets and mice with WT and P/V mutants of the paramyxovirus Simian Virus 5

P/V gene substitutions convert the non-cytopathic paramyxovirus Simian Virus 5 (SV5), which is a poor inducer of host cell responses in human tissue culture cells, into a mutant (P/V-CPI−) that induces high levels of apoptosis, interferon (IFN)-beta, and proinflammatory cytokines. However, the effec...

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Detalles Bibliográficos
Autores principales: Capraro, Gerald A., Johnson, John B., Kock, Nancy D., Parks, Griffith D.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574746/
https://www.ncbi.nlm.nih.gov/pubmed/18456301
http://dx.doi.org/10.1016/j.virol.2008.03.034