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Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3

Inhibitor of apoptosis (IAP) proteins have a crucial role in apoptosis, through negative regulation of caspases in species from fruitflies to mammals. In Caenorhabditis elegans, however, no IAP homolog or caspase inhibitor has been identified, calling into question how the cell-killing caspase CED-3...

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Detalles Bibliográficos
Autores principales: Geng, Xin, Shi, Yong, Nakagawa, Akihisa, Yoshina, Sawako, Mitani, Shohei, Shi, Yigong, Xue, Ding
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574878/
https://www.ncbi.nlm.nih.gov/pubmed/18776901
http://dx.doi.org/10.1038/nsmb.1488