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N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta

BACKGROUND: The organic solute transporter (OSTα-OSTβ) is a heteromeric transporter that is expressed on the basolateral membrane of epithelium in intestine, kidney, liver, testis and adrenal gland and facilitates efflux of bile acids and other steroid solutes. Both subunits are required for plasma...

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Detalles Bibliográficos
Autores principales: Soroka, Carol J, Xu, Shuhua, Mennone, Albert, Lam, Ping, Boyer, James L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575201/
https://www.ncbi.nlm.nih.gov/pubmed/18847488
http://dx.doi.org/10.1186/1471-2121-9-57