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Lysozyme M deficiency leads to an increased susceptibility to Streptococcus pneumoniae-induced otitis media

BACKGROUND: Lysozyme is an antimicrobial innate immune molecule degrading peptidoglycan of the bacterial cell wall. Lysozyme shows the ubiquitous expression in wide varieties of species and tissues including the tubotympanum of mammals. We aim to investigate the effects of lysozyme depletion on pneu...

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Detalles Bibliográficos
Autores principales: Shimada, Jun, Moon, Sung K, Lee, Haa-Yung, Takeshita, Tamotsu, Pan, Huiqi, Woo, Jeong-Im, Gellibolian, Robert, Yamanaka, Noboru, Lim, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575207/
https://www.ncbi.nlm.nih.gov/pubmed/18842154
http://dx.doi.org/10.1186/1471-2334-8-134