Genetic Control of Variegated KIR Gene Expression: Polymorphisms of the Bi-Directional KIR3DL1 Promoter Are Associated with Distinct Frequencies of Gene Expression

Natural killer (NK) cells play an important role in the detection and elimination of tumors and virus-infected cells by the innate immune system. Human NK cells use cell surface receptors (KIR) for class I MHC to sense alterations of class I on potential target cells. Individual NK cells only expres...

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Detalles Bibliográficos
Autores principales: Li, Hongchuan, Pascal, Véronique, Martin, Maureen P., Carrington, Mary, Anderson, Stephen K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575236/
https://www.ncbi.nlm.nih.gov/pubmed/19008943
http://dx.doi.org/10.1371/journal.pgen.1000254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575236/
https://www.ncbi.nlm.nih.gov/pubmed/19008943
http://dx.doi.org/10.1371/journal.pgen.1000254

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