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Pre-miRNA Loop Nucleotides Control the Distinct Activities of mir-181a-1 and mir-181c in Early T Cell Development

BACKGROUND: Mature miRNAs can often be classified into large families, consisting of members with identical seeds (nucleotides 2 through 7 of the mature miRNAs) and highly homologous ∼21-nucleotide (nt) mature miRNA sequences. However, it is unclear whether members of a miRNA gene family, which enco...

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Detalles Bibliográficos
Autores principales: Liu, Gwen, Min, Hyeyoung, Yue, Sibiao, Chen, Chang-Zheng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575382/
https://www.ncbi.nlm.nih.gov/pubmed/18974849
http://dx.doi.org/10.1371/journal.pone.0003592