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Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

Tuberculosis (TB) is characterized by a tight interplay between Mycobacterium tuberculosis and host cells within granulomas. These cellular aggregates restrict bacterial spreading, but do not kill all the bacilli, which can persist for years. In-depth investigation of M. tuberculosis interactions wi...

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Detalles Bibliográficos
Autores principales: Peyron, Pascale, Vaubourgeix, Julien, Poquet, Yannick, Levillain, Florence, Botanch, Catherine, Bardou, Fabienne, Daffé, Mamadou, Emile, Jean-François, Marchou, Bruno, Cardona, Pere-Joan, de Chastellier, Chantal, Altare, Frédéric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575403/
https://www.ncbi.nlm.nih.gov/pubmed/19002241
http://dx.doi.org/10.1371/journal.ppat.1000204