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Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence
Tuberculosis (TB) is characterized by a tight interplay between Mycobacterium tuberculosis and host cells within granulomas. These cellular aggregates restrict bacterial spreading, but do not kill all the bacilli, which can persist for years. In-depth investigation of M. tuberculosis interactions wi...
Autores principales: | Peyron, Pascale, Vaubourgeix, Julien, Poquet, Yannick, Levillain, Florence, Botanch, Catherine, Bardou, Fabienne, Daffé, Mamadou, Emile, Jean-François, Marchou, Bruno, Cardona, Pere-Joan, de Chastellier, Chantal, Altare, Frédéric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575403/ https://www.ncbi.nlm.nih.gov/pubmed/19002241 http://dx.doi.org/10.1371/journal.ppat.1000204 |
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