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Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays
INTRODUCTION: Breast cancer metastasis is a complex, multi-step biological process. Genetic mutations along with epigenetic alterations in the form of DNA methylation patterns and histone modifications contribute to metastasis-related gene expression changes and genomic instability. So far, these ep...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575535/ https://www.ncbi.nlm.nih.gov/pubmed/18638373 http://dx.doi.org/10.1186/bcr2121 |