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Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays

INTRODUCTION: Breast cancer metastasis is a complex, multi-step biological process. Genetic mutations along with epigenetic alterations in the form of DNA methylation patterns and histone modifications contribute to metastasis-related gene expression changes and genomic instability. So far, these ep...

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Detalles Bibliográficos
Autores principales: Rodenhiser, David I, Andrews, Joseph, Kennette, Wendy, Sadikovic, Bekim, Mendlowitz, Ariel, Tuck, Alan B, Chambers, Ann F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575535/
https://www.ncbi.nlm.nih.gov/pubmed/18638373
http://dx.doi.org/10.1186/bcr2121