Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity

INTRODUCTION: Exogenous prolactin is mitogenic and antiapoptotic in breast cancer cells, and overexpression of autocrine prolactin cDNA in breast cancer cell lines has been shown to stimulate their growth and to protect against chemotherapy-induced apoptosis. We examined the effects of the 'pur...

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Detalles Bibliográficos
Autores principales: Howell, Sacha J, Anderson, Elizabeth, Hunter, Tom, Farnie, Gillian, Clarke, Robert B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575541/
https://www.ncbi.nlm.nih.gov/pubmed/18681966
http://dx.doi.org/10.1186/bcr2129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575541/
https://www.ncbi.nlm.nih.gov/pubmed/18681966
http://dx.doi.org/10.1186/bcr2129

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