Cargando…
Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity
INTRODUCTION: Exogenous prolactin is mitogenic and antiapoptotic in breast cancer cells, and overexpression of autocrine prolactin cDNA in breast cancer cell lines has been shown to stimulate their growth and to protect against chemotherapy-induced apoptosis. We examined the effects of the 'pur...
Autores principales: | Howell, Sacha J, Anderson, Elizabeth, Hunter, Tom, Farnie, Gillian, Clarke, Robert B |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575541/ https://www.ncbi.nlm.nih.gov/pubmed/18681966 http://dx.doi.org/10.1186/bcr2129 |
Ejemplares similares
-
Prolactin receptor signaling induces acquisition of chemoresistance and reduces clonogenicity in acute myeloid leukemia
por: Cuesta-Casanovas, Laia, et al.
Publicado: (2023) -
An artefact in clonogenic assays of bleomycin cytotoxicity.
por: Twentyman, P. R.
Publicado: (1977) -
Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells
por: Chebly, Alain, et al.
Publicado: (2021) -
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
por: Singh, Jagdeep K, et al.
Publicado: (2013) -
Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity
por: Janeckova, Lucie, et al.
Publicado: (2016)