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Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep
INTRODUCTION: Acute lung injury often complicates severe sepsis. In Gram-negative sepsis, bacterial endotoxin activates both coagulation and inflammation. Enhanced lung vascular pressures and permeability, increased extravascular lung water content and deteriorated gas exchange characterize ovine en...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575593/ https://www.ncbi.nlm.nih.gov/pubmed/18702832 http://dx.doi.org/10.1186/cc6985 |