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Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep

INTRODUCTION: Acute lung injury often complicates severe sepsis. In Gram-negative sepsis, bacterial endotoxin activates both coagulation and inflammation. Enhanced lung vascular pressures and permeability, increased extravascular lung water content and deteriorated gas exchange characterize ovine en...

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Detalles Bibliográficos
Autores principales:	Waerhaug, Kristine, Kuklin, Vladimir N, Kirov, Mikhail Y, Sovershaev, Mikhail A, Langbakk, Bodil, Ingebretsen, Ole C, Ytrehus, Kirsti, Bjertnaes, Lars J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575593/ https://www.ncbi.nlm.nih.gov/pubmed/18702832 http://dx.doi.org/10.1186/cc6985

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