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Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory and destructive joint disease characterized by overexpression of pro-inflammatory/pro-destructive genes and other activating genes (for example, proto-oncogenes) in the synovial membrane (SM). The gene expression in disease is often c...

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Detalles Bibliográficos
Autores principales: Huber, René, Hummert, Christian, Gausmann, Ulrike, Pohlers, Dirk, Koczan, Dirk, Guthke, Reinhard, Kinne, Raimund W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575612/
https://www.ncbi.nlm.nih.gov/pubmed/18721452
http://dx.doi.org/10.1186/ar2485