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Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis

INTRODUCTION: Despite the advent of biological therapies for the treatment of rheumatoid arthritis, there is a compelling need to develop alternative therapeutic targets for nonresponders to existing treatments. Soluble receptors occur naturally in vivo, such as the splice variant of the cell surfac...

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Detalles Bibliográficos
Autores principales: Jin, Pei, Zhang, Juan, Sumariwalla, Percy F, Ni, Irene, Jorgensen, Brett, Crawford, Damian, Phillips, Suzanne, Feldmann, Marc, Shepard, H Michael, Paleolog, Ewa M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575619/
https://www.ncbi.nlm.nih.gov/pubmed/18593464
http://dx.doi.org/10.1186/ar2447