Sarcospan reduces dystrophic pathology: stabilization of the utrophin–glycoprotein complex

Mutations in the dystrophin gene cause Duchenne muscular dystrophy and result in the loss of dystrophin and the entire dystrophin–glycoprotein complex (DGC) from the sarcolemma. We show that sarcospan (SSPN), a unique tetraspanin-like component of the DGC, ameliorates muscular dystrophy in dystrophi...

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Detalles Bibliográficos
Autores principales: Peter, Angela K., Marshall, Jamie L., Crosbie, Rachelle H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575773/
https://www.ncbi.nlm.nih.gov/pubmed/18981229
http://dx.doi.org/10.1083/jcb.200808027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575773/
https://www.ncbi.nlm.nih.gov/pubmed/18981229
http://dx.doi.org/10.1083/jcb.200808027

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