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Toll-like receptor 4 restricts retinal progenitor cell proliferation

Retinal neurogenesis ceases by the early postnatal period, although retinal progenitor cells (RPCs) persist throughout life. In this study, we show that in the mammalian eye, the function of Toll-like receptor 4 (TLR4) extends beyond regulation of the innate immune response; it restricts RPC prolife...

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Detalles Bibliográficos
Autores principales: Shechter, Ravid, Ronen, Ayal, Rolls, Asya, London, Anat, Bakalash, Sharon, Young, Michael J., Schwartz, Michal
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575781/
https://www.ncbi.nlm.nih.gov/pubmed/18981228
http://dx.doi.org/10.1083/jcb.200804010