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Memo–RhoA–mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells

Actin assembly at the cell front drives membrane protrusion and initiates the cell migration cycle. Microtubules (MTs) extend within forward protrusions to sustain cell polarity and promote adhesion site turnover. Memo is an effector of the ErbB2 receptor tyrosine kinase involved in breast carcinoma...

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Detalles Bibliográficos
Autores principales: Zaoui, Kossay, Honoré, Stéphane, Isnardon, Daniel, Braguer, Diane, Badache, Ali
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575782/
https://www.ncbi.nlm.nih.gov/pubmed/18955552
http://dx.doi.org/10.1083/jcb.200805107