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Memo–RhoA–mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells
Actin assembly at the cell front drives membrane protrusion and initiates the cell migration cycle. Microtubules (MTs) extend within forward protrusions to sustain cell polarity and promote adhesion site turnover. Memo is an effector of the ErbB2 receptor tyrosine kinase involved in breast carcinoma...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575782/ https://www.ncbi.nlm.nih.gov/pubmed/18955552 http://dx.doi.org/10.1083/jcb.200805107 |