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Intra-Articular Fms-Like Tyrosine Kinase 3 Ligand Expression Is a Driving Force in Induction and Progression of Arthritis

BACKGROUND: One of the hallmarks of rheumatoid arthritis (RA) is hyperplasia and inflammation of the synovial tissue being characterized by in situ occurrence of highly differentiated leukocytes. Fms-like tyrosine kinase 3 (Flt3) has a crucial role in hematopoiesis, regulation of cell proliferation,...

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Detalles Bibliográficos
Autores principales: Dehlin, Mats, Bokarewa, Maria, Rottapel, Robert, Foster, Simon J., Magnusson, Mattias, Dahlberg, Leif E., Tarkowski, Andrej
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575855/
https://www.ncbi.nlm.nih.gov/pubmed/18982072
http://dx.doi.org/10.1371/journal.pone.0003633