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Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population
BACKGROUND: CALM1 gene encodes calmodulin (CaM), an important and ubiquitous eukaryotic Ca(2+)-binding protein. Several studies have indicated that a deficient CaM function is likely to be involved in the pathogenesis of osteoarthritis (OA). Using a convincing genome-wide association study, a Japane...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576056/ https://www.ncbi.nlm.nih.gov/pubmed/18940010 http://dx.doi.org/10.1186/1471-2350-9-91 |