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Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population

BACKGROUND: CALM1 gene encodes calmodulin (CaM), an important and ubiquitous eukaryotic Ca(2+)-binding protein. Several studies have indicated that a deficient CaM function is likely to be involved in the pathogenesis of osteoarthritis (OA). Using a convincing genome-wide association study, a Japane...

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Detalles Bibliográficos
Autores principales: Shi, Dongquan, Ni, Haijian, Dai, Jin, Qin, Jianghui, Xu, Yong, Zhu, Lunqing, Yao, Chen, Shao, Zhenxing, Chen, Dongyang, Xu, Zhihong, Yi, Long, Ikegawa, Shiro, Jiang, Qing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576056/
https://www.ncbi.nlm.nih.gov/pubmed/18940010
http://dx.doi.org/10.1186/1471-2350-9-91