Human H(+)ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1

The vacuolar-type ATPase (H(+)ATPase) is a ubiquitously expressed multisubunit pump whose regulation is poorly understood. Its membrane-integral a-subunit is involved in proton translocation and in humans has four forms, a1–a4. This study investigated two naturally occurring point mutations in a4�...

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Detalles Bibliográficos
Autores principales: Su, Ya, Blake-Palmer, Katherine G., Sorrell, Sara, Javid, Babak, Bowers, Katherine, Zhou, Aiwu, Chang, Simon H., Qamar, Seema, Karet, Fiona E.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576143/
https://www.ncbi.nlm.nih.gov/pubmed/18632794
http://dx.doi.org/10.1152/ajprenal.90258.2008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576143/
https://www.ncbi.nlm.nih.gov/pubmed/18632794
http://dx.doi.org/10.1152/ajprenal.90258.2008

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