Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells

BACKGROUND: Aggresomes are juxtanuclear inclusion bodies that have been proposed to represent a general cellular response to misfolded proteins in mammalian cells. Yet, why aggresomes are not a pathological characteristic of protein misfolding diseases is unclear. Here, we investigate if a misfolded...

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Detalles Bibliográficos
Autores principales: Beaudoin, Simon, Goggin, Kevin, Bissonnette, Cyntia, Grenier, Catherine, Roucou, Xavier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576168/
https://www.ncbi.nlm.nih.gov/pubmed/18937858
http://dx.doi.org/10.1186/1471-2121-9-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576168/
https://www.ncbi.nlm.nih.gov/pubmed/18937858
http://dx.doi.org/10.1186/1471-2121-9-59

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