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Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells
BACKGROUND: Aggresomes are juxtanuclear inclusion bodies that have been proposed to represent a general cellular response to misfolded proteins in mammalian cells. Yet, why aggresomes are not a pathological characteristic of protein misfolding diseases is unclear. Here, we investigate if a misfolded...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576168/ https://www.ncbi.nlm.nih.gov/pubmed/18937858 http://dx.doi.org/10.1186/1471-2121-9-59 |