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The role of positive selection in determining the molecular cause of species differences in disease

BACKGROUND: Related species, such as humans and chimpanzees, often experience the same disease with varying degrees of pathology, as seen in the cases of Alzheimer's disease, or differing symptomatology as in AIDS. Furthermore, certain diseases such as schizophrenia, epithelial cancers and auto...

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Detalles Bibliográficos
Autores principales: Vamathevan, Jessica J, Hasan, Samiul, Emes, Richard D, Amrine-Madsen, Heather, Rajagopalan, Dilip, Topp, Simon D, Kumar, Vinod, Word, Michael, Simmons, Mark D, Foord, Steven M, Sanseau, Philippe, Yang, Ziheng, Holbrook, Joanna D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576240/
https://www.ncbi.nlm.nih.gov/pubmed/18837980
http://dx.doi.org/10.1186/1471-2148-8-273