Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays

BACKGROUND: Genomic hybridization platforms, including BAC-CGH and genotyping arrays, have been used to estimate chromosome copy number (CN) in tumor samples by detecting the relative strength of genomic signal. The methods rely on the assumption that the predominant chromosomal background of the sa...

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Detalles Bibliográficos
Autores principales: Gardina, Paul J, Lo, Ken C, Lee, Walter, Cowell, John K, Turpaz, Yaron
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576260/
https://www.ncbi.nlm.nih.gov/pubmed/18928532
http://dx.doi.org/10.1186/1471-2164-9-489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576260/
https://www.ncbi.nlm.nih.gov/pubmed/18928532
http://dx.doi.org/10.1186/1471-2164-9-489

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