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Recovering probabilities for nucleotide trimming processes for T cell receptor TRA and TRG V-J junctions analyzed with IMGT tools

BACKGROUND: Nucleotides are trimmed from the ends of variable (V), diversity (D) and joining (J) genes during immunoglobulin (IG) and T cell receptor (TR) rearrangements in B cells and T cells of the immune system. This trimming is followed by addition of nucleotides at random, forming the N regions...

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Detalles Bibliográficos
Autores principales: Bleakley, Kevin, Lefranc, Marie-Paule, Biau, Gérard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576266/
https://www.ncbi.nlm.nih.gov/pubmed/18831754
http://dx.doi.org/10.1186/1471-2105-9-408