MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism

INTRODUCTION: A functional polymorphism within MDM2, SNP309 T>G, has been linked to early onset cancer. This study examined clinical associations of breast cancer with SNP309 in a Scottish Caucasian population and investigated additional MDM2 intron 1 polymorphisms. METHODS: Intron 1 of MDM2 was...

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Detalles Bibliográficos
Autores principales: Paulin, Fiona EM, O'Neill, Mary, McGregor, Gillian, Cassidy, Andrew, Ashfield, Alison, Ali, Clinton W, Munro, Alastair J, Baker, Lee, Purdie, Colin A, Lane, David P, Thompson, Alastair M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576335/
https://www.ncbi.nlm.nih.gov/pubmed/18828900
http://dx.doi.org/10.1186/1471-2407-8-281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576335/
https://www.ncbi.nlm.nih.gov/pubmed/18828900
http://dx.doi.org/10.1186/1471-2407-8-281

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