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Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells

Small RNAs targeted to gene promoters in human cells have been shown to modulate both transcriptional gene suppression and activation. However, the mechanism involved in transcriptional activation has remained poorly defined, and an endogenous RNA trigger for transcriptional gene silencing has yet t...

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Detalles Bibliográficos
Autores principales: Morris, Kevin V., Santoso, Sharon, Turner, Anne-Marie, Pastori, Chiara, Hawkins, Peter G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576438/
https://www.ncbi.nlm.nih.gov/pubmed/19008947
http://dx.doi.org/10.1371/journal.pgen.1000258