Key Role of Splenic Myeloid DCs in the IFN-αβ Response to Adenoviruses In Vivo

The early systemic production of interferon (IFN)-αβ is an essential component of the antiviral host defense mechanisms, but is also thought to contribute to the toxic side effects accompanying gene therapy with adenoviral vectors. Here we investigated the IFN-αβ response to human adenoviruses (Ads)...

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Detalles Bibliográficos
Autores principales: Fejer, György, Drechsel, Lisa, Liese, Jan, Schleicher, Ulrike, Ruzsics, Zsolt, Imelli, Nicola, Greber, Urs F., Keck, Simone, Hildenbrand, Bernd, Krug, Anne, Bogdan, Christian, Freudenberg, Marina A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576454/
https://www.ncbi.nlm.nih.gov/pubmed/19008951
http://dx.doi.org/10.1371/journal.ppat.1000208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576454/
https://www.ncbi.nlm.nih.gov/pubmed/19008951
http://dx.doi.org/10.1371/journal.ppat.1000208

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