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Inhibition of retinal neovascularization by siRNA targeting VEGF(165)

PURPOSE: To investigate whether vector-based vascular endothelial growth factor 165 (VEGF)(165) targeted siRNA expression system (pSilencer(siVEGF)) could inhibit VEGF(165) expression in vitro and suppresses retinal neovascularization in the murine model of oxygen-induced retinopathy. METHODS: pSile...

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Detalles Bibliográficos
Autores principales: Xia, Xiao-bo, Xiong, Si-qi, Song, Wei-tao, Luo, Jie, Wang, Yu-ke, Zhou, Rong-rong
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576481/
https://www.ncbi.nlm.nih.gov/pubmed/18978955