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Structural Constraints for the Binding of Short Peptides to Claudin-4 Revealed by Surface Plasmon Resonance
Claudin family transmembrane proteins play an important role in tight junction structure and function in epithelial cells. Among the 24 isoforms identified in mice and humans, claudin-4 and -3 serve as the receptor for Clostridium perfringens enterotoxin (Cpe). The second extracellular loop (Ecl2) o...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576538/ https://www.ncbi.nlm.nih.gov/pubmed/18782762 http://dx.doi.org/10.1074/jbc.M803548200 |