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Structural Constraints for the Binding of Short Peptides to Claudin-4 Revealed by Surface Plasmon Resonance

Claudin family transmembrane proteins play an important role in tight junction structure and function in epithelial cells. Among the 24 isoforms identified in mice and humans, claudin-4 and -3 serve as the receptor for Clostridium perfringens enterotoxin (Cpe). The second extracellular loop (Ecl2) o...

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Detalles Bibliográficos
Autores principales: Ling, Jun, Liao, Hailing, Clark, Robin, Wong, Mandy Sze Man, Lo, David D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576538/
https://www.ncbi.nlm.nih.gov/pubmed/18782762
http://dx.doi.org/10.1074/jbc.M803548200