The Sushi Domains of Secreted GABA(B1) Isoforms Selectively Impair GABA(B) Heteroreceptor Function

GABA(B) receptors are the G-protein-coupled receptors for γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain. GABA(B) receptors are promising drug targets for a wide spectrum of psychiatric and neurological disorders. Receptor subtypes exhibit no pharmacological difference...

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Detalles Bibliográficos
Autores principales: Tiao, Jim Y., Bradaia, Amyaouch, Biermann, Barbara, Kaupmann, Klemens, Metz, Michaela, Haller, Corinne, Rolink, Antonius G., Pless, Elin, Barlow, Paul N., Gassmann, Martin, Bettler, Bernhard
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576543/
https://www.ncbi.nlm.nih.gov/pubmed/18765663
http://dx.doi.org/10.1074/jbc.M804464200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576543/
https://www.ncbi.nlm.nih.gov/pubmed/18765663
http://dx.doi.org/10.1074/jbc.M804464200

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