Partially Irreversible Inactivation of Mitochondrial Aldehyde Dehydrogenase by Nitroglycerin

Mitochondrial aldehyde dehydrogenase (ALDH2) may be involved in the biotransformation of glyceryl trinitrate (GTN), and the inactivation of ALDH2 by GTN may contribute to the phenomenon of nitrate tolerance. We studied the GTN-induced inactivation of ALDH2 by UV/visible absorption spectroscopy. Dehy...

Descripción completa

Detalles Bibliográficos
Autores principales: Beretta, Matteo, Sottler, Astrid, Schmidt, Kurt, Mayer, Bernd, Gorren, Antonius C. F.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Enzyme Catalysis and Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576553/
https://www.ncbi.nlm.nih.gov/pubmed/18786921
http://dx.doi.org/10.1074/jbc.M804001200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576553/
https://www.ncbi.nlm.nih.gov/pubmed/18786921
http://dx.doi.org/10.1074/jbc.M804001200

Ejemplares similares