A Comparative Structural Bioinformatics Analysis of the Insulin Receptor Family Ectodomain Based on Phylogenetic Information

The insulin receptor (IR), the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor-related receptor (IRR) are covalently-linked homodimers made up of several structural domains. The molecular mechanism of ligand binding to the ectodomain of these receptors and the resulting activa...

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Detalles Bibliográficos
Autores principales: Rentería, Miguel E., Gandhi, Neha S., Vinuesa, Pablo, Helmerhorst, Erik, Mancera, Ricardo L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577065/
https://www.ncbi.nlm.nih.gov/pubmed/18989367
http://dx.doi.org/10.1371/journal.pone.0003667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577065/
https://www.ncbi.nlm.nih.gov/pubmed/18989367
http://dx.doi.org/10.1371/journal.pone.0003667

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