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The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines

BACKGROUND: Genistein is an isoflavonoid present in soybeans that exhibits anti-carcinogenic properties. The issue of genistein as a potential anti-cancer drug has been addressed in some papers, but comprehensive genomic analysis to elucidate the molecular mechanisms underlying the effect elicited b...

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Detalles Bibliográficos
Autores principales: Regenbrecht, Christian RA, Jung, Marc, Lehrach, Hans, Adjaye, James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577110/
https://www.ncbi.nlm.nih.gov/pubmed/18847459
http://dx.doi.org/10.1186/1755-8794-1-49