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Impaired Autoimmune T Helper 17 Cell Responses Following DNA Vaccination against Rat Experimental Autoimmune Encephalomyelitis

BACKGROUND: We have previously shown that vaccination with DNA encoding the encephalitogenic peptide myelin oligodendrocyte glycoprotein (MOG)(91–108) (pMOG) suppresses MOG(91–108)-induced rat Experimental Autoimmune Encephalomyelitis (EAE), a model for human Multiple Sclerosis (MS). The suppressive...

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Detalles Bibliográficos
Autores principales: Andersson, Åsa, Isaksson, Magnus, Wefer, Judit, Norling, Anna, Flores-Morales, Amilcar, Rorsman, Fredrik, Kämpe, Olle, Harris, Robert A., Lobell, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577303/
https://www.ncbi.nlm.nih.gov/pubmed/18997868
http://dx.doi.org/10.1371/journal.pone.0003682