Overexpression of the LexA-regulated tisAB RNA in E. coli inhibits SOS functions; implications for regulation of the SOS response

The DNA damage induced SOS response in Escherichia coli is initiated by cleavage of the LexA repressor through activation of RecA. Here we demonstrate that overexpression of the SOS-inducible tisAB gene inhibits several SOS functions in vivo. Wild-type E. coli overexpressing tisAB showed the same UV...

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Detalles Bibliográficos
Autores principales: Weel-Sneve, Ragnhild, Bjørås, Magnar, Kristiansen, Knut Ivan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577331/
https://www.ncbi.nlm.nih.gov/pubmed/18832374
http://dx.doi.org/10.1093/nar/gkn633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577331/
https://www.ncbi.nlm.nih.gov/pubmed/18832374
http://dx.doi.org/10.1093/nar/gkn633

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